Distillations

Gene editing promises to revolutionize medicine. But how safe is safe enough for the patients testing these therapies?

When the United States and Mexico resolved their beef.

Living in a world nearly free of polio, it’s difficult to imagine what it was like when almost every summer children fell ill, became paralyzed, and sometimes died from a disease people didn’t understand and couldn’t control.

Join Distillations podcast hosts Lisa Berry Drago and Alexis Pedrick as Science History Institute staff members share their favorite objects from our museum, archival, and library collections.

Many of us think pumping is a new part of motherhood, but some fascinating 19th-century objects from our collection show the practice has been around (in some form) for a long time.

One woman’s quest to end her pain. 

Part 3: Searching for Meaning in Kensington. 

Part 2: Synanon and the Tunnel Back to the Human Race.

Part 1: The Narcotic Farm and the Promise of Salvation.

The strange, sometimes sickening things we’ve done to understand what goes on inside our guts.

The latest painkiller revival has left a trail of bodies, with no end in sight.

Fermentation is the key to many of the life-saving drugs we have today.

This episode highlights a bottle of mid-20th century vitamins that are actually caffeine pills in disguise.

Warfarin, a drug that started life 70 years ago as a rat poison, remains one of the most important treatments for heart disease and stroke. But for all its success the anticoagulant remains as dangerous as its origin suggests.

Do cats mess with your brain?

Too much coffee actually can kill you, but that’s not the most important thing about the chemistry of coffee.

Candy stores in the 19th century sold sweets as deadly as they were delicious.

A globe-hopping doctor and a weird amphibian produce a fast, inexpensive pregnancy test.

Using 21st-century medicine to maintain a 300-year-old way of life.

In a time of warring empires and transoceanic voyages, sailors dreaded scurvy more than any other disease.

John Harvey Kellogg’s Battle Creek Sanitarium was at the intersection of new ideas of religion, health, and nutrition.

For more than a century ozone therapy has been a source of false hope for the sick and ill-gotten gains for the crooked.

The unnatural history of a carbonated drink.

An early dietitian set out to prove that vegetarian cooking was good for the body. Others who followed tried to show it could be tasty and even good for the soul.

When does self-experimentation cross the line?

A molecule used in antifreeze may one day heal damaged spinal cords. 

A simple invention that saved lives and led to the discovery of a hidden form of life.

Once upon a time all births were natural. A lot has happened since then.

A look back at how outsiders have influenced medicine throughout time.

The story of Louis Pasteur and the development of the rabies vaccine.

Dive into the world of nixtamalization and discover the ancient chemical practices behind your taco.

In the 1920s author Paul de Kruif turned science into an adventure story.

How one man’s youthful rebellion may unlock a cure for cancer.

Using chemistry to put a lid on unsavory practices.

Blood is powerful, but it can also be dangerous.

Rethinking the ethics of organ transplants.

Sophisticated drugs have enabled those with HIV to live long lives—as long as they take their medication.

Anthropologist Jason Pine offers an up-close view of methamphetamine culture in small-town America.

Relics from a lab hint at centuries spent trying to solve diabetes.

Health fads come and health fads go, though few were as downright odd as the 1920s’ and 1930s’ craze for yeast cakes.

Ten years later and thousands of miles away, Hurricane Katrina lives on.

For much of the 20th century the instrument of many murders, suicides, and accidental deaths could be bought at the local drugstore.

We explore how faith, desire for easy answers, and lack of trust in medical science shape two modern trends. 

Sophisticated drug cocktails have dramatically changed the fates of people with HIV. Yet in many ways we’re treading water.

What do ancient Egyptian mummies, early modern medicines, a 19th-century philosopher, and a 21st-century chemist have in common?

This episode of Distillations examines what is perhaps our most underrated sense, and ponders what life would be like without it.

Through war and peace doctors struggle to prevent disease. The Civil War was no exception, except in the case of one doctor who did his best to spread sickness.

Can a tool that helped create atomic weapons become a tool for healing?

Have you ever wondered how chicken nuggets are made?

Mix a 19th-century chemist with a road builder in South America. Add cows and boil. (Bring a strong stomach to this story.)

No, not that kind of pen—this is the kind of pen that saves lives. Discover the history of the EpiPen.

During the American Civil War the North and South developed different strategies to treat malaria.

In this episode we take a look at a disease feared for millennia: cancer.

Join us for the third installment of The Stages of Life, spotlighting the chemistry found in old age.

Join us for the second installment of The Stages of Life, spotlighting the chemistry found in adulthood.

Today's episode begins the three-part series The Stages of Life. To kick things off, we spotlight the chemistry found in childhood.

Chlorpromazine, once celebrated as the “chemical lobotomy,” shifted medicine’s approach to mental illness.

Today your taste buds take center stage.

On today’s show we peel back our skin. 

We wrap up the three-part series A Day in the Life, today spotlighting the common chemistry of night. 

We continue the three-part series A Day in the Life, today spotlighting the common chemistry of noontime.

We begin the three-part series A Day in the Life, today spotlighting the common chemistry of morning.

We wrap up the three-part series Blood, Sweat, and Tears. This week: tears. 

Continuing the three-part series Blood, Sweat, and Tears. This week: sweat.

Neither medicine nor food, the vitamin pill was born in the early 20th century and came of age during World War II. Now, vitamins are here to stay—and so is the controversy that swirls around them.

No doubt, babies are adorable. But on today’s show we examine some more serious aspects of parenthood.

Sneezing, itchy eyes, runny nose? On this episode we look at allergies.

Amphetamine didn’t cure anything, but it did make you feel better. Chemist Gordon Alles faced this paradox after patenting his discovery in 1932.

On today’s episode of Distillations we go straight to the source. . .your DNA.

The controversy around animal magnetism.

Thomas R. Tritton reviews Carl Zimmer’s A Planet of Viruses.

Today’s show explores one of our favorite senses: taste. 

This week we bring you some of our favorite segments from past Distillations episodes.

John Hickman reviews Siddhartha Mukherjee’s The Emperor of All Maladies: A Biography of Cancer.

The impact of the Civil War can still be seen politically, socially, and economically, but its influence on medicine is often obscured.

A 19th-century chemist was the first to raise the alarm about adulterated food.

This week we look at diagnostic and therapeutic applications of nuclear medicine.

Thin became “in” during the 1920s, and the calorie became a vital tool in the battle to lose weight. Yet before becoming a fashion necessity, the calorie had a decidedly less glamorous role in agriculture, laboratories, and factories.

In the 1970s The Dow Chemical Company undertook a massive campaign to raise awareness about the importance of safety both within and outside of the workplace.

In the 19th century chemical oblivion replaced liquor, opiates, and bleeding as the numbing agent of choice in the surgeon’s toolkit.

This week, we celebrate April Fools’ Day with a little medical trickery.

In this episode we learn about yoga and acupuncture.

Today’s show will have your skin crawling...literally.

Insulin was first used to treat diabetes in the 1920s. Since then doctors have used a multitude of tests to screen for the disease.

Absinthe, an alcoholic drink introduced to France in the 1840s, developed a decadent though violent reputation. To some the drink symbolized creativity and liberation, and to others, madness and despair. One thing was certain: more than science was behind European responses to its influence.

In 1856 William Palmer, or Palmer the Poisoner, was tried and convicted in Victorian England’s trial of the century. The case also introduced forensic chemistry as a means of conviction.

Before pharmaceuticals existed, all medicines had to come from natural sources—like plants. This week we focus on such remedies.

At the turn of the 20th century diphtheria was a feared childhood illness, until a new treatment method came to the rescue.

In the late 19th century cod-liver oil was proclaimed the cure for many ailments. One problem: the oil’s foul taste.

On this week’s episode of Distillations we’re talking about what the nose knows.

Whether it’s preventing illness by vaccines or avoiding germs, this episode is about getting sick and staying healthy.

In this episode of Distillations we clarify common misconceptions about food.

David Caruso reviews Leo B. Slater’s War and Disease: Biomedical Research on Malaria in the 20th Century.

Meet sodium chloride, the latest nutritional villain. But are the alternatives scarier than the substance it’s replacing? A brief history about a “terrifying” food.

Rise and Shine! Today we look at some of the most essential elements of a satisfying breakfast.

David Healy reviews Nicholas Rasmussen’s book On Speed: The Many Lives of Amphetamine.

Distillations takes a look at the history and chemistry of dentistry. 

From antiquity to the present, lead has taken on many roles—from artificial sweetener, to paint ingredient, to modern health scourge. 

Aspirin has had a long history as a pain reliever. But only in the 1970s did scientists begin to uncover its chemical secrets.